Aachener Verfahrenstechnik - Computational Systems Biotechnology


Univ.-Prof. Dr. rer. nat. Wolfgang Wiechert

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The chair of "Computational Systems Biotechnology" (AVT.CSB) headed by Prof. Dr. Wolfgang Wiechert was founded in 2011 as a member of AVT. Simultaneously, Prof. Wiechert is director of the institute IBG-1 (Biotechnology) at Forschungszentrum Jülich. The major research area of IBG-1 is applied systems bio(techno)logy with a special focus on method development for quantitative biology.

Since 2011 Prof Wiechert teaches at RWTH Aachen University. His Chair “Computational Systems Biotechnology“ is part of the AVT. Modeling, simulation and data analysis in systems biology are central aspects of his teaching activities.

The institute IBG-1:Biotechnology at the research Center Jülich is developing biotechnological production processes for platform chemicals, fine chemicals, pharmaceuticals and proteins. The department of „Systems Biotechnology“ headed by Prof. Wiechert is using a systems biology measurement platform (metabolomics, fluxomics, proteomics) in combination with engineering approaches (process engineering, automation, modeling) for a targeted process development at shortened time scales.

In the Jülich institute both whole cell and cell free systems are developed. Central tools for this purpose are quantitative bioanalytical methods and mathematical models used both for the detailed characterization of complex biochemical networks in living cells and for investigating whole bioprocesses. The rational development of enzyme toolboxes for combinatorial biosynthesis paves the way to new chiral molecules in industrial biotechnology and new synthetic metabolic pathways can be established (Synthetic Biology). These activities are complemented by the design of microfluidic devices for single cell analysis accomplished by the development of new fluorescence biosensors.


Forckenbeckstraße 51

Postal Code:



Phone: +49 2461 615557
Email: w.wiechert@fz-juelich.de

  • System
    • System Analysis
      • Technical
      • Economical
      • Ecological
      • Social Science
    • Life Cycle Assessment
    • Innovation and Exnovation in the Transformation of Structures
    • Well to Wheel
    • Acceptance of Critical Infrastructure
    • Technology - based system analysis
  • Resources
    • Renewable Energy
      • Wind
      • Solar
      • Geothermics
      • Biomass
      • Water
    • Materials
      • Water
      • Inorganic Substances
      • CO2
      • Recyling of Polymers
      • Biomass
  • Infrastructure
    • Storage
      • Battery
      • Chemical Storage
      • Thermal Storage
      • Overarching topics
    • Grids & Networks
      • Integration
      • Flexibilization
      • Security
  • Conversion
    • Supply
      • Non-Fossil Carbon Sources
      • Fuel Cells
      • Electrolysis
      • Power Plant Technologies
      • Photochemical, Solarthermal & Electrochemical Processes
      • Energy to Chemicals
    • Consumption
      • Residental Buildings
      • Industry
      • Transport & Agriculture

Profile Area ECPE

The provision of sustainable energy and materials is clearly one of the major global challenges which were identified in the future strategy of RWTH Aachen University. The profile area Energy, Chemical & Process Engineering (ECPE) addresses the two most important pathways to achieve this goal: Improvements in energy and material efficiency and the transition to renewable sources.

More information on the profile area's key topics can be found here.

RWTH Aachen Profile Areas

RWTH Aachen University is convinced that in order to solve today's complex and multi-faceted problems, universities have to develop appropriate, integrated approaches. The Profile Areas are designed to address interdisciplinary topics and thus to enhance the University’s capability to engage in significant research activities and take on large-scale projects.


Are you interested in the Profile Area ECPE? Do you have suggestions? Feel free to contact the Profile Area coordinator Stefan Sterlepper: